The liver receives ~70% of its blood flow and ~50% of its oxygen from the portal vein, independent of the hepatic artery. When the hepatic artery occludes, portal venous flow maintains viability. The kidneys, by contrast, have segmental arteries that are functional end arteries with no dual supply — occlusion causes permanent wedge infarcts. Clinically: hepatic artery aneurysm, celiac occlusion, or accidental hepatic artery ligation is often survivable; renal artery embolism causes permanent infarction. This hepatic dual supply concept is also why TIPS (creating a portohepatic shunt) can reduce hepatic parenchymal oxygenation.
Key: Liver = dual supply (hepatic artery + portal vein). Hepatic artery occlusion alone → rarely infarcts. Kidney = end arteries → always infarcts per segment.